Seeking Novel in vivo Models to Understand Pathological Mechanisms in Human Disease

Daiichi Sankyo, a global pharmaceutical company, is seeking novel in vivo models to understand pathological mechanisms in human disease. Indications of interest include microcirculatory disorders (e.g. INOCA, type II myocardial infarction, coronary microvascular dysfunction, etc.), dry aged-macular diseases, psychiatric diseases (neuroinflammatory related model for “CIAS of schizophrenia” and / or “MDD”) and neurodegenerative diseases.

Approaches of Interest:

• Mouse models are of interest for all indications
• Rabbit, pig or other large animal models are of high interest for studies relating to dry aged-macular diseases 
• Models should have the ability to evaluate drug compounds and study the mechanism of action of the compounds at their target

Out of Scope:

• Lipopolysaccharide-induced neuroinflammation and zebrafish models
• Research around 3D cell models and computational models

Developmental Stages of Interest:

• Basic research through to established animal models is of interest

Submission Information

Submission of one page, 200-300 word briefs are encouraged, along with any optional supplementary information e.g. relevant publications. In submitting to this campaign, you confirm that your submission contains only non-confidential information. Our client is also open to novel research proposals which can be outlined using this submission form.

Opportunity for Collaboration

Daiichi Sankyo is open to a range of collaboration opportunities, with the most appropriate outcome being decided on a case-by-case basis. Example outcomes include licensing assets, project/PhD funding, and research collaborations.