P-selectin antagonist Bicycles: a Novel Chemical Modality to Explore the Role of P-selectin in Disease

BicycleTx Ltd. (Bicycle®) has developed an extensive library of small molecule peptidic compounds called ‘Bicycles’, which are constrained bicyclic peptides that bind with high affinity and selectivity to targets. Bicycles combine the pharmacological properties characteristic of biologics with the manufacturing and pharmacokinetic advantages of small molecules. Bicycle® is seeking to establish research collaborations to fully characterise these tools, and explore their potential application across different therapeutics areas with a disease area agnostic...