Neuron and Axon Regeneration in Cases of Glial Scarring in Chronic Neurodegeneration

This campaign has been commissioned by an international Japanese pharmaceutical company who combat diseases with a combination of ground‑breaking technology and biology, with an extensive track record of academic collaboration. They are seeking a solution that achieves neuron regeneration or axon regeneration within glial scarring in animal models.

Regeneration within glial scarring caused by the following diseases are of interest to the client:

• Stroke
• Spinal cord injury
• Traumatic brain injury
• Parkinson’s disease
• Charcot-Marie-Tooth disease
• Huntington disease
• Peripheral nerve injury, in chronic stage (not acute phase)
• Amyotrophic Lateral Sclerosis

They are also seeking functional motor recovery of animal models with these targets. All modalities with these targets will be considered, such as: 

• Adeno-associated virus
• Nucleic acid, protein, antibody, bio-materials, or small compound

Out of Scope:

• Cell therapy projects (i.e. replenishment with in vitro reprogrammed cells)
• Alzheimer’s Disease and Dementia are not of interest
• Non‑mammalian animal models are not within scope

Stage of Development:

Pre‑clinical and late pre‑clinical solutions will be considered.

Submission Information:

Submission of one-page summaries of Research Projects, Technology Briefs, Academic Profiles, Centres of Excellence and Spin-Outs are encouraged. Alternatively, please fill out an application form available here.