Seeking Innovative Therapeutic Targets, Drugs, Disease Mechanisms and Technologies in Neuroscience

Takeda Pharmaceutical are launching an open innovation initiative, inviting researchers to submit their ideas and technologies across five different focus areas, up to £60k / €70k / $100k (AUD). Summarised below are the interests of Takeda relating to Therapeutic Targets, Drugs, Disease Mechanisms and Technologies for Neuroscience. In the attached application form, each of these topics have been expanded upon to give further detail of proposals.

Submissions should be relevant to one or more of the following titles: 

• REF #1 Proposal and validation study of novel therapeutic approaches for rare/intractable diseases associated with neurodegeneration; e.g. ALS, Huntington’s disease and ataxias.
• REF #2 Molecular mechanism research of disease pathology or reverse translational research with clinical data and samples in frontotemporal dementia, Down’s syndrome with cognitive decline, or postoperative cognitive dysfunction.
• REF #3 Proposal of novel therapeutic approaches and validation studies for neural disorders which do not fall upon the above (#1 and #2).
• REF #4 Novel therapeutic approaches to prevent or recover age-related disturbance of neuronal function; e.g.sleep/circadian rhythm, waste clearance, BBB integrity, inflammation, organelle homeostasis, DNA damage, sensory system.
• REF #5 Definition of novel disease concepts based on biomarker strategy for strict patient stratification, followed by establishment of pathophysiologically-relevant cellular model, and therapeutic approach including gene therapy.
• REF #6 Development of new research tools, drug assay systems or drug modalities for neurodegenerative disease or rare disease with neurodegenerative pathology.
• REF #7 Novel drug targets, therapeutic concepts and research tool for aberrant glia-neuron network involved in neurodegenerative diseases such as FTLD, PD, ALS, AD.

Global Eligibility: 

Only submissions from Europe and Australia will be eligible for this campaign.

How to Apply: 

To view more details on each area of interest seeking proposals for funding, download an application form here. To submit your proposal, please visit discover.in-part.com, register, and submit as a Research Project under the appropriate Discover campaign.